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Friday, 26 September 2014 00:00

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Friday, 26 September 2014 00:00

AVIVAX-FTM:

Live Attenuated New Castle Disease Virus Vaccine

COMPOSITION

AVIVAX-FTM is a freeze-dried live attenuated New Castle disease viral vaccine prepared from the ‘F’ strain of the virus. The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

New Castle disease is caused by specified viruses of the avian paramyxovirus type 1(APMV-1) serotype of the genus Rubulavirus belonging to the family Paramyxoviridae. There are nine types of avian paramyxoviruses designated APMV-1 to APMV-9. New castle disease virus has been designated APMV-1. Since its recognition in 1926 the disease has been regarded as being endemic in many countries. Prophylactic vaccination is practised in all but a few of the countries that produce poultry on a commercial scale.

AVIVAX-FTM is a lentogenic vaccine prepared from the ‘F’ strain after subjection to selection and cloning. Being a live vaccine AVIVAX-FTM induces a stronger immune response against New castle disease compared to the inactivated vaccines.

 

INDICATIONS

For the active immunization of healthy poultry against New castle disease.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with the corresponding sterile diluent. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. Administer two drops, one into each nostril using a suitable pipette to birds of over 14 days old. Primary inoculation should be followed by a second one six weeks later. CONTRA-INDICATIONS, WARNINGS for Veterinary use only. Do not vaccinate un-healthy birds. Do not use if seal is broken or package is damaged.

STORAGE

Store at -20°C. (Freezer). Under these conditions, the shelf life is 2 years. If stored at between +2°C and +8°C (refrigerator) the shelf life is one month. Once the vaccine has been reconstituted, it must be used immediately and any remaining quantity discarded.

PRESENTATION

100-dose vials packed together with the corresponding diluent.

Friday, 26 September 2014 00:00

BLUVAX TM

Live Attenuated Bluetongue Disease Vaccine

COMPOSITION

BLUVAXTM is a freeze-dried, live attenuated Bluetongue Disease vaccine prepared from 7 strains of Bluetongue virus. The strains in the vaccine are 1,2,3,4,8,12, and 134.The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

Bluetongue is an infectious, non-contagious, insect-borne viral disease of sheep and other domestic and wild ruminants. Clinical signs of disease are uncommon in domestic animals and are generally found only in sheep and some wild ruminants. Symptoms range from sub-clinical to an acute, febrile response characterised by inflammation and congestion, leading to facial oedema and haemorrhages, and ulceration of the mucous membranes. The tongue may show intense hyperaemia, become swollen and oedematous and protrude from the mouth. Hyperaemia may extend to other parts of the body, particularly the groin, axilla and perineum. There is often severe muscle degeneration. Dermatitis may cause wool breaks. Sheep may become lame as a result of coronitis, inflammation of the coronary band of the hoof , or skeletal myopathy.

Bluetongue virus is a member of the Orbivirus genus of the family Reoviridae. Within the genus there are 14 serogroups. The bluetongue serogroup contains 24 serotypes.
BLUVAX TM is prepared by serial passage of strains 1,2,3,4,8,12, and 134 of the field virus in embryonated chicken eggs. Following serial passage, virulence is attenuated and concomitantly, viruses replicate to lower titres in sheep resulting in stimulation of protective immunity in the animals without causing disease in the animals. This also ensures low enough titres in the blood to prevent infection of feeding insects.

INDICATIONS

For the vaccination of healthy sheep as an aid in prevention and control of Bluetongue Disease caused by the strains 1,2,3,4,8,12,and 134 which are the major cause of the disease in the East and Central African region.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with the corresponding sterile diluent. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. Administer via the subcutaneous route to sheep over the age of 3 months at the rate of 1ml per animal. Vaccinate wool sheep at about three weeks before shearing. Revaccination should be carried out yearly.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy animals. This multi-strain vaccine is recommended for use in sheep only. Do not vaccinate pregnant ewes. All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered.

STORAGE

Store at -20°C. (Freezer). Under these conditions the shelf-life is 2 years. If stored at between +2°C and +8°C (refrigerator) the shelf life is one month. Once the vaccine has been reconstituted, it must be used immediately and any remaining quantity discarded.

PRESENTATION

50-, 100-, and 300-dose vials packed together with the corresponding diluent.

Friday, 26 September 2014 00:00

CONTAVAX TM:

Live Attenuated Contagious Bovine Pleuropneumonia Vaccine

COMPOSITION

CONTAVAX TM: is a freeze-dried live attenuated Contagious Bovine Pleuropneumonia vaccine prepared from Mycoplasma mycoides mycoides strain T 1/44 a naturally mild strain isolated in 1951 by Sherrif and Piercy in Tanzania. The seed virus is attenuated by egg-passage. The diluent is used to re-hydrate the freeze-dried component. Each vaccinal dose upon reconstitution contains a minimum of 107 viable mycoplasmas.

PROPERTIES

Contagious Bovine Pleuropneumonia (CBPP) is a disease of cattle caused by Mycoplasma mycoides subspecies mycoides small colonies (bovine biotype). The disease is manifested by anorexia, fever, and respiratory symptoms such as dyspnoea, polypnoea cough, and nasal discharges. The main problems for control or eradication are the frequent occurrence of subacute or symptomless infections and the persistence of chronic carriers after the clinical phase.
CONTAVAX TM: is produced according to the OIE standards and as a result the vaccine exhibits remarkable safety characteristics with very minimal post-vaccination reactions.

INDICATIONS

For the active immunization of healthy cattle against Contagious Bovine Pleuropneumonia.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with the corresponding sterile diluents. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. Administer via the subcutaneous route at the tip of the tail to cattle of at least 6 months of age at the rate of 0.5ml per animal. Vaccination should be carried out annually.
CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy animals. All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered. Routine vaccination should be carried out only in cattle over 6 months of age, but in the face of an outbreak all age groups can be vaccinated.

STORAGE

Store at -20°C (Freezer). Under these conditions, the shelf life is 2 years. If stored at between +2°C and +8°C (refrigerator) the shelf life is one month. Once the vaccine has been reconstituted, it must be used immediately and any remaining quantity discarded.

PRESENTATION

50-, and100-dose vials packed together with the corresponding diluents.

Friday, 26 September 2014 00:00

FOWLVAX TM

Inactivated Salmonella gallinarum (Fowl typhoid) Vaccine

COMPOSITION

FOWLVAX TM: is a multi-strain inactivated Fowl typhoid vaccine prepared from Salmonella gallinarum. The strains included are CN 175, 176, 177, 178, and 179.

PROPERTIES

Fowl typhoid is a disease of chickens caused by Salmonella gallinarum and is more often observed in the later growing period and in mature stock. The clinical signs resemble those of septicaemia, with inappetence and, eventually, death.

INDICATIONS

For the active immunization of healthy chicken against Fowl typhoid.

DOSAGE AND ADMINISTRATION

Shake well before use. Vaccination should be done using sterile needle and syringe to avoid contamination. Administer to birds via intramuscular injection in the thigh or breast muscles at the rate of 1ml per bird.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy birds. This preparation is strictly for use in poultry only. All vaccines may occasionally cause anaphylactic reactions in some birds. If this occurs adrenaline should be administered.

STORAGE

Store at +4°C. (Refrigerator). DO NOT FREEZE. If stored at between +2°C and +8°C (refrigerator) the shelf life is one year.
Once the vaccine bottle has been broached it must be used immediately and any remaining quantity discarded.

PRESENTATION

50-, 100-, and 300-dose vials.

Friday, 26 September 2014 00:00

ORFVAX TM

Live Attenuated Contagious Pustular Dermatitis Virus Vaccine

COMPOSITION

ORFVAX TM is a freeze-dried live attenuated Contagious Pustular Dermatitis viral vaccine. The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

Contagious Pustular Dermatitis (ORF) is a highly infectious viral disease of sheep and goats characterised by the development of pustular and scabby lesions on the muzzle and lips. The disease is caused by a dermatotropic ungulate pox virus. The virus withstands drying and is capable of surviving at room temperature for at least 15 years. The disease is commonest in lambs 3-6 months of age although adult animals can be severely affected.

INDICATIONS

For the active immunisation of healthy sheep and goats against Contagious pustular dermatitis.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with 30 mls the corresponding sterile diluent. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. The vaccine should be applied to scarified skin on the inside of the thigh. This is done by making 3 to 4 short superficial scratches about ½” apart with a sterile hypodermic needle. These scratches should break the skin but should not cause bleeding. The vaccine is applied using a small piece of cotton wool moistened with the reconstituted vaccine. A mild local reaction occurs within one week and immunity develops within 14 days. Annual revaccination is recommended.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy animals. Ewes should not be vaccinated later than 4 weeks before lambing or when they have not weaned their lambs. Lambs under 6 weeks of age should not be vaccinated. Contagious pustular dermatitis (ORF) is infectious to humans and therefore the vaccine must be handled with care, preferably with gloves. All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered.

STORAGE

Store at -20°C. (Freezer). Under these conditions, the shelf life is 2 years. If stored at between +2°C and +8°C (refrigerator) the shelf life is one month. Once the vaccine has been reconstituted, it must be used immediately and any remaining quantity discarded.

PRESENTATION

100-dose vials packed together with the corresponding diluent.

Friday, 26 September 2014 00:00

RIFTVAX TM

Live Attenuated Rift Valley Fever Virus Vaccine

COMPOSITION

RIFTVAX TM is a freeze-dried live attenuated Rift Valley Fever vaccine prepared from Smithburn’s attenuated strain of RVF virus. The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

Rift Valley Fever Virus is the aetiological agent of a peracute or acute zoonotic disease of domestic ruminants. The disease is caused by a single serotype of the mosquito-borne bunyavirus of the genus Phlebovirus and occurs in climatic conditions favoring the breeding of mosquito vectors. It is characterized by liver damage and is most severe in sheep, goats and cattle, in which it produces abortions in pregnant animals and a high mortality rate in the newborn. Older non-pregnant animals, although susceptible to infection, are more resistant to clinical disease.
Humans are susceptible to infection by handling infected material and through transmission by mosquito vectors.
RIFTVAX TM has proved itself, with more than 35 years of successful use all over Africa and the Middle East, as a safe and efficient means of preventing RVF virus infections in cattle, sheep, and goats.

INDICATIONS

For the active immunisation of healthy cattle, sheep, and goats against Rift Valley Fever.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with the corresponding sterile diluent. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. Administer via the subcutaneous route to animals of all ages at the rate of 2ml for cattle and 1ml for sheep and goats.
Annual revaccination is recommended and should be carried out at least one month before the seasons when outbreaks of the disease are expected.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy animals. Abortions may occur in some pregnant animals following vaccination. All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered. Rift Valley Fever is infectious to humans (zoonosis) and therefore the vaccine must be handled with care.

STORAGE

Store at -20°C. (Freezer). Under these conditions, the shelf life is 2 years. If stored at between +2°C and +8°C (refrigerator) the shelf life is one month. Once the vaccine has been reconstituted, it must be used immediately and any remaining quantity discarded.

PRESENTATION

100 dose vials packed together with the corresponding diluent.

Friday, 26 September 2014 00:00

RINDERVAX TM

Live Attenuated Rinderpest Virus Vaccine

COMPOSITION

RINDERVAX TM is a freeze-dried live attenuated Rinderpest virus vaccine prepared from the Kabete ‘O’ strain of the virus. The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

Rinderpest is an acute, fatal disease of domestic cattle and buffalo caused by a mobillivirus in the family Paramyxoviridae. The virus also affects sheep, goats and Asiatic pigs and a large variety of free-living species within the order Artiodactyla, although not always in a clinically apparent form. Clinically, the disease is characterised by pyrexia, the progressive development of shallow erosions on the gums, tongue, cheeks, and hard palate, together with serous or mucopurulent ocular and nasal discharges. Alimentary tract involvement is marked by the development of severe  diarrhoea.
RINDERVAX TM was developed at the former East African Veterinary Research Organization (now KEVEVAPI) by serial passage of the virulent bovine rinderpest strain kabete ‘O’. It is safe for use in cattle, buffalo, sheep and goats of all ages.

INDICATIONS

For the active immunisation of healthy cattle against Rinderpest.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with the corresponding sterile diluent. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. Administer via the subcutaneous route to animals of at least 6 months of age at the rate of 2ml per animal. The resulting immunity is lifelong and therefore animals should be vaccinated only once in a lifetime.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy animals. All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered.

STORAGE

Store at -20°C. (Freezer). Under these conditions, the shelf life is 2 years. If stored at between +2°C and +8°C (refrigerator) the shelf life is one month. Once the vaccine has been reconstituted, it must be used immediately ( within 2 hours if chilled or within 1 hour in case not chilled) and any remaining quantity discarded.

PRESENTATION

50-, and 100-dose vials packed together with the corresponding diluent. 

Friday, 26 September 2014 00:00

AVIVAX-L TM

Live Attenuated New Castle Disease Virus Vaccine

COMPOSITION

AVIVAX-LTM is a freeze-dried live attenuated New Castle disease viral vaccine prepared from the La Sota strain of the virus. The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

New Castle disease is caused by specified viruses of the avian paramyxovirus type 1(APMV-1) serotype of the genus Rubulavirus belonging to the family Paramyxoviridae. There are nine types of avian paramyxoviruses designated APMV-1 to APMV-9. New castle disease virus has been designated APMV-1. Since its recognition in 1926 the disease has been regarded as being endemic in many countries. Prophylactic vaccination is practised in all but a few of the countries that produce poultry on a commercial scale.

AVIVAX-L TM is a lentogenic vaccine prepared from the La Sota strain after subjection to selection and cloning. Being a live vaccine AVIVAX-L TM induces a stronger immune response against New castle disease compared to the inactivated vaccines.

INDICATIONS

For the active immunization of healthy poultry against New castle disease.

DOSAGE AND ADMINISTRATION

AVIVAX-LTM is administered orally via drinking water. Withdraw drinking water for at least 3 hours prior to vaccination. Reconstitute the vaccine using water free from chlorine and detergents as shown below.

AGE OF BIRDS 

200 DOSE PACK
(For 200 birds) 

 500DOSE PACK
(For 500 birds)

 4 Days to 3 Weeks

 1-2 Litres of water

 2.5 to 5 Litres of water

 4 to 8 Weeks

 4 Litres of water

 10 Litres of water

 Over 8 Weeks

 8 Litres of water

 20 Litres of water

 

 

 

 

 

 

 Ensure all birds have access to the medicated drinking water within a period of 2 hours.
Primary inoculation should be followed by a second one six weeks later

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not vaccinate un-healthy birds. Do not use if seal is broken or package is damaged. STORAGE Store at -20°C. (Freezer). Under these conditions, the shelf life is 2 years. If stored at between +2°C and +8°C (refrigerator) the shelf life is one month.
Once the vaccine has been reconstituted, it must be used within two hours and any remaining quantity discarded.

PRESENTATION

200- and 500-dose vials.

Friday, 26 September 2014 00:00

CAPRIVAX TM

Inactivated Contagious Caprine Pleuropneumonia Vaccine

COMPOSITION

CAPRIVAXTM is an inactivated Contagious Caprine Pleuropneumonia vaccine prepared from Mycoplasma capricolum subspecies capripneumoniae (Mccp), originally known as the F38 biotype. The vaccine contains lyophilised Mccp suspended in saponin.Each vaccinal dose contains a minimum of 0.15 mg of mycoplasma.

PROPERTIES

Contagious Caprine Pleuropneumonia (CCPP) is a major cause of loss in many countries in Africa and Asia which contain a total goat population of more than 250 million. Classical, acute CCPP is caused by Mycoplasma capricolum subsp. Capripneumoniae (Mccp), first isolated and shown to cause CCPP in Kenya, and subsequently it has been isolated in the Sudan, Tunisia, Oman, Turkey, Chad, Uganda, and Ethiopia. CAPRIVAX TM has proved itself, with more than 10 years of successful use all over Africa and the Middle East, as a safe and efficient means of preventing CCPP in goats. The vaccine is produced according to strict OIE standards and as a result it exhibits remarkable safety characteristics with very minimal post-vaccination reactions.

INDICATIONS

For the active immunisation of healthy goats against Contagious Caprine Pleuropneumonia.

DOSAGE AND ADMINISTRATION

Shake well before use. Vaccination should be done using sterile needle and syringe to avoid contamination. Administer to animals of over 3 months of age via subcutaneous injection at the rate of 1ml per animal. Revaccination should be carried out every 6 months.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy animals. This preparation is strictly for use in goats only. All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered.
Routine vaccination should be carried out only in goats over 3 months of age, but in the face of an outbreak animals from the age of 2 months can be vaccinated.

STORAGE

Store at +4°C. (Refrigerator). DO NOT FREEZE. If stored at between +2°C and +8°C (refrigerator) the shelf life is one year. Once the vaccine bottle has been broached it must be used immediately and any remaining quantity discarded.

PRESENTATION

50 and 100 dose vials.

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Kenya Veterinary Vaccines Production Institute

P.O. BOX 53260 00200 
Head Office, Embakasi off Enterprise Road, Road A,
NAIROBI, KENYA

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